Use of Hibiscus sabdariffa in Ameliorating Anaemia in Wister Rats Induced with Phenylhydrazine

Background and Objective: Hibiscus sabdariffa L. is a medicinal plant that is a member of the known worldwide for treating different diseases. This study is aimed at evaluating the effects of Hibiscus sabdariffa aqueous leaf extraction cellular elements of phenylhydrazine-induced anaemia in rats (i.e., haemolyticanaemia). Materials and Methods: Three groups comprised of control group (8), anaemic group (8) and the treated group (10). The aqueous extract of Hibiscus sabdariffa was administered in constant doses of 200 kg/b.wt., for 14 days. At the end of the feeding requirement through cardiac puncture blood samples for haematological analyses were collected into clean sample bottles containing Ethylenediaminetetraacetic acid (EDTA) at 1.5-2 mg of blood. Results: The results revealed that there was a significant increase (p<0.01) in Haemoglobin concentration (Hb) and Packed Cell Volume (PCV) caused by the aqueous extract in the haemolytic anaemic rats. However, the extract did not cause any noticeable effect on Mean Corpuscular Haemoglobin Concentration (MCHC) and total white blood cells (TWBC) compared with that of the normal control rats. Conclusion: It was found that consumption of the aqueous extract of Hibiscus sabdariffa leaves extract may alleviate anaemic conditions and improve oxygen-carrying capacity of red cells as well as boost the immune system.